Research Articles
Powering Discovery: A Comprehensive Guide to Evident Software for Microbiome Research and Clinical Trials
This article provides a complete roadmap for researchers, scientists, and drug development professionals utilizing Evident software for microbiome study power analysis.
Robust Covariance Estimation in Biomedical Research: Methods, Applications, and Validation for Clinical Data Analysis
This article provides a comprehensive evaluation of robust covariance estimation methods tailored for researchers and drug development professionals.
False Positives in Microbiome Differential Abundance Analysis: A Critical Evaluation for Biomedical Researchers
This article provides a comprehensive evaluation of false positive rates (FPR) in statistical methods for differential abundance (DA) analysis of microbiome data.
Powering Microbiome Discovery: A Practical Guide to Dirichlet-Multinomial Power Analysis for Clinical and Taxonomic Studies
This comprehensive guide addresses the critical need for robust statistical power calculations in microbiome and taxonomic data analysis, where high-dimensional, compositional count data is the norm.
Beyond the Noise: A Practical Guide to Small-Sample Microbiome Research for Robust Biomarker Discovery
This article provides a comprehensive framework for designing, analyzing, and validating microbiome studies constrained by small sample sizes, a common yet critical challenge in biomedical research.
Power in the Gut: DS-FDR vs. Benjamini-Hochberg for Microbiome Differential Abundance
This article provides a comprehensive analysis of the power characteristics of the Data-adaptive Structure-adaptive False Discovery Rate (DS-FDR) procedure compared to the classic Benjamini-Hochberg (BH) method in microbiome differential abundance...
DNA/RNA Shield: The Game-Changer for Room Temperature Microbiome Sample Preservation and Stabilization
This article provides a comprehensive guide for researchers and drug development professionals on DNA/RNA Shield technology for stabilizing microbiome samples at room temperature.
Beyond Contamination: The Essential Guide to DNA-Free Reagents for Accurate Microbiome Research
This comprehensive guide explores the critical role of DNA-free reagents in microbiome DNA extraction.
A Complete Guide to DNA-free Equipment Decontamination Protocols for Next-Generation Research
This article provides a comprehensive, modern framework for eliminating DNA contamination from laboratory collection equipment, critical for high-sensitivity genomic and diagnostic workflows.
The Essential Guide to DNA Extraction QC for Robust Microbiome Research: From Basics to Best Practices
This comprehensive guide addresses the critical role of DNA extraction quality control (QC) in ensuring the reliability, reproducibility, and validity of microbiome study data.